abstract |
Intercalator compounds are provided which are comprised of intercalatornmoieties, or substituted intercalator moieties, having one or more functionalized chains,nor moieties, and which compounds provide a high affinity for binding to the DNAnmolecule and show reduced self-quenching, while providing superior transport kinetics.nThe compounds have been found to provide enhanced fluorescence when bound to anDNA molecule within a fluorescent flow cytometry environment which is about eight tonten times brighter in fluorescence than "bis" structure conventional intercalating agentsnand other known intercalating agents utilized in flow cytometry environment. |