http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1406907-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b9237fdf6dca9ac365fc5166858e7862 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D515-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4995 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D515-22 |
| filingDate | 2002-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c32f680e4b1d1137c0e1b586dbd1ef8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0529793c72dc1011dae79389d822a25f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0596be321cb2979c06d105823138e1dc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e201c7dc269302774d33989fc7b0fd69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6281f55472736259486cba224ef250bb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5de3cb66e26cf96ee6a144e0f103173a |
| publicationDate | 2004-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1406907-A1 |
| titleOfInvention | New antitumoral derivatives of et-743 |
| abstract | The present invention provides a compound of the general formula Ia : nwherein R 2 , R 4 , R 5 are each independently selected of H, C(=O)R', C(=O)OR', P=O(OR') 2 , substituted or unsubstituted C 1 -C 18 alkyl, substituted or unsubstituted C 2 -C 18 alkenyl, substituted or unsubstituted C 2 -C 18 alkynyl, substituted or unsubstituted aryl; nwherein R 1 is C(=O)R" or C(=O)OR", and R" is an optionally substituted alkyl with at least 4 carbon atoms or an optionally substituted alkenyl, wherein the optional substituents are selected from aryl or heterocyclic; or R" is derived from an optionally protected amino acid; nwherein R 6 and R 7 are both =O and the dotted lines indicate a quinone ring, or R 6 is -OR 3 , where R 3 is H, C(=O)R', C(=O)OR' substituted or unsubstituted C 1 -C 18 alkyl, substituted or unsubstituted C 2 -C 18 alkenyl, substituted or unsubstituted C 2 -C 18 alkynyl, substituted or unsubstituted aryl, R 7 is H, and the dotted lines indicate a phenyl ring; nwherein X 2 , X 3 , X 4 , X 5 , X 6 are independently selected of H, OH, OR', SH, SR', SOR', SO 2 R', C(=O)R', C(=O)OR', NO 2 , NH 2 , NHR', N(R') 2 , NHC(=O)R', CN, halogen, substituted or unsubstituted C 1 -C 24 alkyl, substituted or unsubstituted C 2 -C 18 alkenyl, substituted or unsubstituted C 2 -C 18 alkynyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaromatic; nwherein X 1 is independently selected of OH, CN, (=O), or H; nwherein each of the R' groups is independently selected from the group consisting of H, OH, NO 2 , NH 2 , SH, CN, halogen, C(=O)H, C(=O)CH 3 , CO 2 H, PO(OR') 2 , substituted or unsubstituted C 1 -C 18 alkyl, substituted or unsubstituted C 2 -C 18 alkenyl, substituted or unsubstituted C 2 -C 18 alkynyl, substituted or unsubstituted aryl; nwherein when R 2 , R 3 , R 4 , and R 5 are substituted, the substituents are each independently selected from the group consisting of OH, OR', SH, SR', SOR', SO 2 R', C(=O)R', C(=O)OR', NO 2 , NH 2 , NHR', N(R') 2 , NHC(O)R', CN, halogen, =O, substituted or unsubstituted C 1 -C 18 alkyl, substituted or unsubstituted C 2 -C 18 alkenyl, substituted or unsubstituted C 2 -C 18 alkynyl, substituted or unsubstituted aryl, substituted or unsubstituted heterocyclic. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10538535-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11713325-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11332480-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11339180-B2 |
| priorityDate | 2001-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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