| abstract |
The present invention is to provide a nitrogen-containingnheterocyclic derivative represented by the general formula (I)nor a pharmaceutically acceptable salt thereof, or a prodrugnthereof, which exerts an excellent inhibitory activity in humannSGLT2 and is useful as an agent for the prevention or treatmentnof a disease associated with hyperglycemia such as diabetes etc.,nor a pharmaceutical composition comprising the same and anpharmaceutical use thereof and a production intermediate thereof.nIn the general formula (I), X 1 and X 3 are N or CH; X 2 is N ornCR 2 ; X 4 is N or CR 3 ; and with the proviso that one or two of X 1 ,nX 2 , X 3 and X 4 are N; and R 1 , R 2 and R 3 are a hydrogen atom etc. |