http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1404678-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9d49b92406663b4d78393463c7f2eb9f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0071 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-409 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-22 |
| filingDate | 2002-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2006-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b6dcc3d31f84b8fe367e9e61cb85337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5bdf540aedb59e6e180975c19b1139a1 |
| publicationDate | 2006-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1404678-B1 |
| titleOfInvention | Water-soluble porphyrin derivatives for photodynamic therapy, their use and manufacture |
| abstract | The invention relates to the chemistry of biologically active compounds, namely, to a new method to prepare water-soluble porphyrin derivatives, particularly chlorin derivatives having general formulae (1). The compounds of the present invention are useful as photosensitizers, as drug substances and optionally in suitable drug products, for the photodynamic therapy of cancer, of infectious and other diseases, as well as for light irradiation treatments in other cases. B is a ring having the structure: where: R1=-CH=CH2, -CH(OAlk)CH3, -CHO, -C(O)CH3; -CH2CH3; -CH(Alk)CH(COAlk)2, -CH2CH(COAlk)2, -CH(Alk)CH2COAlk, -CH(Alk)CH2CH(OH)CH3, -CH2CH2CH(OH)CH3 R2=-CH3, -CHO, -CH(OH)Alk, -CH=CHAlk, CH2OH, CH2OAlk; R3=H or lower alkyl; G=hydrophilic organic amine (f.ex. N-methyl-D-glucamine and other amino-group containing carbohydrate derivatives, TRIS, aminoacids, oligopeptides). Alk=alkyl substituent. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2354096-A1 |
| priorityDate | 2001-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 131.