| abstract |
The present invention is directed to a pharmaceutical composition fornadministering active ingredients that cause upper gastrointestinal tractnirritation, such as polyphosphonates. Said dosage form comprises the irritatingnactive ingredient and an ion exchange resin. Said dosage form protects the tissuesnof the buccal cavity, pharynx, esophagus, and the stomach from erosion andnulceration due to exposure of the irritating active ingredient to said tissues. |