http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1395825-B1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_26e19c12ac350fc1c0c02bcf301685e6 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-564 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-564 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
filingDate | 2002-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2007-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d434072e85f12d28c695fb104b73abd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4fb4756c9ef279c1672401fffecef3cc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca6592df5812a6d0e02ebab3c2e04d37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa14e9822c7e1ba7784a5c8b2075aaca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c031ff8ce63048c2a6747cdc733430fd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad088abdbc0df356f7d8b9a7ecf6dd9e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d1048276e3e6d75cad5a9d00f34b79b |
publicationDate | 2007-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-1395825-B1 |
titleOfInvention | Method for detecting rheumatoid arthritis-specific autoantibodies |
abstract | A method for detecting anti-filaggrin-autoantibodies specific to rheumatoid arthritis in a biological sample, by providing a filaggrin with no citrulline residues (FNC) having an arginine residue or a filaggrin peptide with no citrulline residues (PFNC) having an arginine residue. Also provided are a citrulline-containing filaggrin (FC) having the peptide sequence of the FNC where some arginine residues have been converted to citrulline residues or a citrulline-containing peptide (PFC) having the peptide sequence of the PFNC, where at least one arginine residue has been converted to a citrulline residue. The sample is contacted with the FNC or PFNC and the FC or PFC, and the resulting immune complexes are detected and quantified, with a value XNC and XC, respectively. Anti-filaggrin-autoantibodies specific to rheumatoid arthritis are determined to be present in the biological sample if the value of XC is greater than the value of XNC. |
priorityDate | 2001-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 69.