| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5d1596f64ec0b2dac5334b2cf05b88bb |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
| filingDate |
2002-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ea1958f37baba770ce4efa6f0fdaefcc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d352754a716295ea7a4bd84c9363534
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eed21eb1a29a2d9e58a74106c449a48d |
| publicationDate |
2004-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1394267-A1 |
| titleOfInvention |
Single nucleotide polymorphisms predictive for cardiovascular disease, adverse drug reactions, and drug efficacy |
| abstract |
The invention provides diagnostic methods and kits including oligo and/ornpolynucleotides or derivatives, including as well antibodies determining whether anhuman subject is at risk of getting adverse drug reaction after statin therapy ornwhether the human subject is a high or low responder or a good a or bad metabolizernof statins. The invention provides further diagnostic methods and kits includingnantibodies determining whether a human subject is at risk for a cardiovascularndisease. Still further the invention provides polymorphic sequences and other genes. n The present invention further relates to isolated polynucleotides encoding anphenotype associated (PA) gene polypeptide useful in methods to identify therapeuticnagents and useful for preparation of a medicament to treat cardiovascular disease orninfluence drug response, the polynucleotide is selected from the group comprising:n SEQ ID 1-168 with allelic variation as indicated in the sequences section containednin a functional surrounding like full length cDNA for PA gene polypeptide and withnor without the PA gene promoter sequence. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007071382-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007128984-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2095127-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007128984-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008060240-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114317726-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007071382-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2095127-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101589309-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012004301-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2405271-A1 |
| priorityDate |
2002-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |