abstract |
Compounds are provided which have the structure: (formula I); wherein Q is C or N; R?2a, R2b, R2c, X¿1 to X7, R?1, R2, R3, R3a, R4¿, A, Y, m, and n are as defined herein, which compounds are useful as antidiabetic, hypolipidemic, and antiobesity agents. The present invention further provides a method for treating obesity and dyslipidemia in mammals including humans through simultaneous inhibition of peroxisome proliferator activated receptor-η (PPARη) and stimulation of peroxisome proliferator activated receptor-α (PPARα). |