abstract |
A medicament for preventive and/or therapeutic treatment of a microbialninfection which comprises as an active ingredient a compound represented by thenfollowing general formula (I):n nwherein, R 1 and R 2 represent hydrogen atom, a halogen atom, hydroxyl group or thenlike, W 1 represents -CH=CH-, -CH 2 O-, -CH 2 CH 2 - or the like; R 3 represents hydrogennatom, a halogen atom, hydroxyl group or an amino group; R 4 represents hydrogen atom,na group of -OZ 0-4 R 5 (Z 0-4 represents an alkylene group, a fluorine-substituted alkylenengroup or a single bond, and R 5 represents a cyclic alkyl group, an aryl group or thenlike); W 2 represents a single bond or -C(R 8 )=C(R 9 )- (R 8 and R 9 represent hydrogen atom,na halogen atom, a lower alkyl group or the like, Q represents an acidic group, but W 2 nand Q may together form vinylidenethiazolidinedione or an equivalent heterocyclicnring; m and n represent an integer of 0 to 2, and q represents an integer of 0 to 3. |