| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5b459ec3f5254c20ccd5ca24931c4610 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D305-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D305-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-337
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J23-44 |
| filingDate |
2002-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f2d4826464ec3e0bf76fb997f4cceb51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e4492de41fa9c506df59050d279ea3b8 |
| publicationDate |
2004-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1389196-A1 |
| titleOfInvention |
Three-step conversion of protected taxane ester to paclitaxel |
| abstract |
The present invention relates to a method of producing paclitaxel from a protected coupled ester compound having a formula: wherein P1 is a hydrogenatable protecting group, comprising deprotecting the 7-O-position and 3'-N-position of the protected coupled ester compound to form a first intermediate compound, benzoylating the first intermediate compound at the 31-N-position thereby to form a second intermediate compound, and deprotecting the second intermediate compound by replacing P¿1? with hydrogen in the presence of an acid. The present invention also provides chemical compounds useful in the production of paclitaxel. |
| priorityDate |
2001-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |