| abstract |
Compounds of Formula (1), Formula (2) or Formula (3) where X is O, S,nor (CR 1 R 1 ) n where n is 0, 1, or 2; Y is anbivalent radical having Formula (4) or Formula (5) where o is an integernfrom 1 to 4 or Y is a bivalent aryl or 5 or 6 membered heteroaryl radicalnhaving to 3 heteroatoms selected from N, S and O, said aryl ornheteroaryl groups being unsubstituted, or substituted with 1 to 3nC 1-6 alkyl or with 1 to 3 C 1-6 fluoroalkyl groups;nand the remaining symbols have the meaning described in the specification,nhave RXR selective retinoid agonist-like activity. |