| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_194c2557f71010b9b248462e23436a12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e5ad8562c578b061df7a2c3aee9d0e24 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F2438-01 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F293-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G75-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F220-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F220-606 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F293-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F297-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F4-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F4-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F212-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F212-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G75-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F220-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F220-54 |
| filingDate |
2003-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d8e8f54515d9679d5b5e4e26b7da8a95
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc2c77bb0cc39cb25a3424efd271e17c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38dbeecee2d294a381e8806cd8c2d0fa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c3f3b321fa1af25b86f2f48defb6a85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b78e341789fdeda17047dea33f96ea5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_358f5afda9823a4ff1a630636935417d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0af01eb700a758cb32bbf025f9931fa1 |
| publicationDate |
2004-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1386935-A1 |
| titleOfInvention |
Dual stimuli-responsive hydrogels and their synthetic methods |
| abstract |
The present invention relates to a process for preparingncopolymer hydrogels with controlled molecular weights andnhaving both thermo- and pH- responsive properties, wherein thenprocess comprises the steps of (a) providing sulfonamide typenstyrenic or (meth)acrylamide-based monomers exhibitingndifferent p K a values; (b) providing poly( N -isopropylacrylamide)nor crosslinked poly( N -isopropylacrylamide - co - methylenenbisacrylamide) hydrogels having thermo-responsive properties;nand (c) providing several hydrogels exhibiting pH-sensitivenproperties and random or block copolymerizations of thensulfonamide type styrenic or (meth)acrylamide-based monomersnprepared in step (a) with N -isopropylacrylamide and/ornmethylene bisacrylamide monomers used in step (b) in a polar ornnon-polar solvent; wherein said steps (b) and (c) are carriednout by controlled/living radical polymerization using alkylnhalides as the initiators and the transition metals withnphosphine or amine ligands as the catalysts. The presentninvention also relates to the copolymer hydrogels made by thenaforesaid process. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101890185-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110903432-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110903432-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101053681-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106519154-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008057163-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10072042-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9982070-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11174325-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100517101-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008057163-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9644042-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012123275-A1 |
| priorityDate |
2002-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |