abstract |
A cyclic amidine derivative represented by thenformula:n n[wherein R 1 , R 2 and R 3 represent hydrogen, C 1-6 alkyl,naryl-C 1-6 alkyl, etc.; R 4 , R 5 and R 7 represent hydrogen,nC 1-6 alkyl, etc.; Z represents 0 or 1; R 6 representsnhydrogen, C 1-6 alkyl, C 1-6 alkyloxycarbonyl, etc.; nnrepresents 1 or 2; Y 1 represents a single bond, -CH 2 -,netc.; Y 2 represents a single bond, -CO-, etc.; Arnrepresents hydrogen, a group represented by thenformula:n n[wherein R 10 -R 14 represent hydrogen, C 1-6 alkyl, hydroxyl,nC 1-6 alkoxy, etc., and R 11 and R 12 or R 12 and R 13 may bondntogether to form a 5- to 8-membered heterocycle], etc.]nor a salt thereof. |