| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e1ac9096a46b26c78e369e5507f95bf |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16H10-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16H50-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16C20-30 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06F19-00 |
| filingDate |
2001-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_00d6db26b3a1661100e3a385bc4ef75d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_75add6fec992ca588c1c0a5ff16250af
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c46c385eccade97543fb2a49923b2a4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f9027557ec8de0fbac029985d5c527b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dbb00ede3c71caa497462d7cd4c019b5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ba532b7ecae2d83239d2e0a1477ff7c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98ba33e37a520a9d166e637aeebb3831
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d34822cad281cd49706c11a48df7cc8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5eff817d6e1963e7dba489a55095bddf |
| publicationDate |
2004-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1386274-A2 |
| titleOfInvention |
Pharmacokinetic tool and method for predicting metabolism of a compound in a mammal |
| abstract |
A system for simulating metabolism of a compound in a mammal is disclosed that includes a metabolism simulation model of a mammalian liver. This model has equations which when executed on a computer, calculate the rate of metabolism of the compound in the cells of the mammalian liver and a rate of transport of the compound into the cells, wherein the simulation model determines an amount of the metabolism product. The rate of metabolism may be a rate of depletion of the compound. The metabolism product may be an amount of the compound remaining after the compound's first passage through the mammalian liver (This is not necessarily limited to first pass, nor would it need to be limited to the liver. Intestinal metabolism could also be modeled). The rate of metabolism may alternatively be a rate of accumulation of a metabolite of the compound. |
| priorityDate |
2000-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |