http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1385421-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_39735fa0a2330b2dd4fe6ed188468ac5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ff81a650b70e913d3b2524b45e4c7320 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-4094 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-14542 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-1473 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-04 |
| filingDate | 2002-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_976db77cc11260c82108a1bfd60b7d74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_718c94eb4950553cfb1834d3e49578f4 |
| publicationDate | 2004-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1385421-A2 |
| titleOfInvention | Identification, diagnosis, and treatment of neuropathologies, neurotoxicities, tumors, and brain and spinal cord injuries using microelectrodes with microvoltammetry |
| abstract | Devices and methods of use thereof for determining the presence and concentration of chemicals in a cell, tissue, organ or organism involve semiderivative voltammetric measurements and chronoamperometric measurements of chemicals, e.g. neurotransmitters, precursors, and metabolites. Methods of diagnosing and/or treating a subject with abnormal levels of neurotransmitters includes those having or at risk of developing epilepsy, diseases of the basal ganglia, athtoid, dystonic diseases, neoplasms, Parkinson's disease, brain injuries, spinal cord injuries, and cancer. Microvoltammetry methods may be performed in vitro, in vivo, or in situ to differentiate white matter from grey matter, diagnose brain tumors, for cancer diagnosis and treatment, and to locate a tumor's position. Broderick probes are used to determine the concentration of the material, e.g. dopamine, norepinephrine, and serotonin, in the brains of patients having epilepsy. In some embodiments of the invention, regions of the brain to be resected or to be targeted for pharmaceutical therapy are identified using Broderick probes. The invention further provides methods of measuring the neurotoxicity of a material by comparing Broderick probe microvoltammograms of a neural tissue in the presence and absence of the material. |
| priorityDate | 2001-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 565.