| abstract |
The present invention is to provide an imidazolidinedione derivativenand oxazolidinedione derivative represented by the following generalnFormula (I) having the chymase and/or tryptase inhibition activityn n[wherein R 1 and R 2 are the same or different, and denote a lower alkyl groupnor a phenyl group, or R 1 and R 2 are taken together to form a ring, R 3 denotesnan optionally substituted naphthyl group or heterocyclic group, A denotesnoxygen or NR 4 (R 4 is hydrogen or optionally substituted lower alkyl group),nor NB 2 R 5 (R 5 is aryl group, and B 2 is carbonyl group or sulfonyl group), andnB 1 denotes a carbonyl group or a sulfonyl group], or a pharmaceuticallynacceptable salt thereof. |