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filingDate 2002-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2007-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1384487-A4
titleOfInvention MEDICAMENTS CONTAINING A GENETICALLY MODIFIED ANTIBODY AGAINST GD3 GANGLIOSIDE
abstract It has been required to establish a highly efficacious therapeutic method for malignant tumor, in particular melanoma, with little side effects and a novel therapeutic method whereby an enhanced therapeutic effect can be achieved in a conventional drug dose. By combining a genetically modified antibody against ganglioside GD3 or its fragment with at least one of a substance capable of activating immunocompetent cells and a substance having an antitumor activity, it is intended to provide drugs having an enhanced therapeutic effect compared with the case of administering either the substance capable of activating immunocompetent cells or the substance having an antitumor activity alone. It is expected that these drugs can relieve the problem of side effects occurring in the conventional single administration.
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