| abstract |
New lipopeptide conjugates are proposed in which a double fatty acid-substituted cysteine is bound via the carboxyl group to a readily water-soluble and physiologically compatible and non-immunogenic polymeric conjugate residue. The new conjugates show very good macrophage-stimulating effects and do not require additional solution mediation. They are suitable for numerous uses, in particular for stimulating macrophages, for stimulating antibody synthesis, for defense against infection, for immunostimulation, in particular against tumors, for the prevention and treatment of septic shock, for wound healing and as an adjuvant for vaccines. |