Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8f32f2cd4cc165637d30b1dd9c3fe7e2 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-24022 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-24222 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-70 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6897 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-70 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6897 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
2001-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_25b1060fe2db7ed062bae424da51299f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_264e961f28f94f69741ffbe23bfa1be9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c8be027f07a5bfc11e832ec07fdb0ac http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a49ac59945cd5e9d3ff3413b14f6e2b |
publicationDate |
2004-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-1373576-A2 |
titleOfInvention |
Nucleic acids and methods for detecting viral infection, uncovering anti-viral drug candidates and determining drug resistance of viral isolates |
abstract |
A nucleic acid construct is provided. The nucleic acid construct includes (a) an expression cassette including: (i) a first polynucleotide region including a 5' NCR sequence of an RNA virus and at least an N-terminal portion of a core sequence of the RNA virus; (ii) a second polynucleotide region including a 3' UTR sequence of the RNA virus and at least a C-terminal portion of a polymerase sequence of the virus; and (iii) a third polynucleotide region encoding a reporter molecule, the third polynucleotide region being flanked by the first and the second polynucleotide regions; and (b) a promoter sequence being operatively linked to the expression cassette in a manner so as to enable a transcription of a minus strand RNA molecule from the expression cassette. |
priorityDate |
2000-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |