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filingDate 2002-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd22e0e577193de9b47d83fc8eb46162
publicationDate 2004-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1372380-A2
titleOfInvention Method for determining the therapeutic efficacy of a medicament against parkinson's disease and/or parkinson syndrome using an fri/fri mouse as a model
abstract The invention relates to a method for determining the therapeutic efficacy of a medicament against Parkinson's disease and/or Parkinson's syndrome, comprising the administration of said medicament to be tested to a (shivering) fri/fri mouse, followed by evaluation of at least one symptom chosen from the following: (5) akinesia; and/or (6) shaking; and/or (7) postural rigidity and instability; and/or (8) deterioration of cognitive functions. The evaluation makes it possible to apprehend an improvement of the clinical state of said animals when the medicament is injected into an fri/fri mouse.
priorityDate 2001-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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