http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1370874-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_21b940d68199e364dfe160850ec76145 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-86 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-80 |
| filingDate | 2002-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92f32f088ceb87d32c9c3a37a1fb517f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c3d1cb99e7a1b4ac2c5acb7c1c33c02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dbcc56adfeb9c89fcbbc56d1e8bdb1cc |
| publicationDate | 2003-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1370874-A2 |
| titleOfInvention | Methods for determining platelet activity with antiplatelet compositions |
| abstract | Methods, compositions and kits are disclosed for the determination of platelet activity on samples such as whole blood that have been affected by exposure to an antiplatelet therapeutic agent such as, <i>e.g.</i>, aspiring or a thienopyridine. A combination is provided in a reaction medium wherein the combination comprises the sample and a particle reagent comprising a GP IIb/IIIa receptor ligand such as fibrinogen covalently attached to particles. The medium further comprises a polyhydroxy aromatic compound and a metal cation. The combination is incubated under conditions for agglutinating the particles. The extent of agglutination of the particles is determined and is related to the platelet function activity of the sample. The methods and compositions have particular application to the detection of platelet sensitivity to therapy using aspirin or a thienopyridine and the assessment of the efficacy of such therapy. |
| priorityDate | 2001-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 185.