abstract |
Described is the use of a microorganism or cell containing anDNA sequence encoding a detectable protein or a proteinncapable of inducing a detectable signal, e.g., a luminescentnor fluorescent protein for the preparation of a diagnosticncomposition for diagnosis and/or visualization of wounded orninflamed tissue or a disease associated therewith. Moreover,ntherapeutic uses are described, wherein said microorganism orncell additionally contain an expressible DNA sequence encodingna protein suitable for therapy, e.g. an enzyme causing cellndeath or digestion of debris. |