http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1366774-A1

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filingDate 2003-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_570223562e7ef0af921cd5ce6e9f8a9b
publicationDate 2003-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1366774-A1
titleOfInvention Bone cement and X-ray contrast agent and methods of manufacturing the same
abstract a) als Polymer oder Copolymer mit daran chemisch gebundenen Verbindungen röntgenopakernElemente ausgebildet ist oder b) als im wesentlichen kugelförmige Polymer- oder Copolymerteilchen mit darin dispergiertennröntgenopaken anorganischen Nanopartikeln der Teilchengröße 3-15 nm, hergestellt durch Polymerisation,nbevorzugt Suspensionspolymerisation, in Gegenwart der Nanopartikel, wobei dienNanopartikel vollständig oder nahezu vollständig von dem (Co)polymermaterial bedeckt sind. A bone cement mixture is described, formed from a polymer component containing an X-ray contrast agent and a monomer component, the X-ray contrast agent a) is designed as a polymer or copolymer with compounds chemically bound to X-ray-opaque elements, or b) as essentially spherical polymer or copolymer particles with X-ray-opaque inorganic nanoparticles of particle size 3-15 nm dispersed therein, produced by polymerization, preferably suspension polymerization, in the presence of the nanoparticles, the nanoparticles being completely or almost completely covered by the (co) polymer material ,
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