http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1364962-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_46a08ff7f3afac37e9d0477377f0a840 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 |
| filingDate | 2002-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d8be7316153dd160a6b1f0196f3a773 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e901313b3210c4e5a6e5d0c1581f9d3c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e8a8f78f0032887b2a778dd44ff5f0dd |
| publicationDate | 2003-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1364962-A1 |
| titleOfInvention | Use of monocarboxylate transporter proteins for thyroid hormone transport |
| abstract | The invention provides a use of a monocarboxylate transporter proteinnor a functional part, derivative and/or analogue thereof for altering transportnof a thyroid hormone or a functional part, derivative and/or analogue thereofnacross a membrane. Said monocarboxylate transporter protein preferablyncomprises MCT-8. An isolated molecule capable of specifically binding at leastnpart of an MCT protein, or at least part of a ligand of an MCT protein, is alsonherewith provided. Regulation of the bioavailability of thyroid hormone in antissue enables interfering with (metabolic) diseases. Hence, the invention alsonprovides pharmaceutical compositions comprising a compound capable ofnbinding said MCT protein, or capable of influencing the binding orntransporting of a ligand of said MCT protein. Methods for treatment of andisease such as a disorder of thyroid metabolism, non-thyroidal illness, obesitynor cardiovascular illness are also provided, as well as bioassays for identifyingnor detecting a candidate drug capable of binding to or influencing at least partnof said MCT protein. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005074996-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005074996-A2 |
| priorityDate | 2002-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 136.