abstract |
A novel fenofibrate-containing composition havingnequivalent bioavailability, when compared to conventionalncapsules, is effective in reducing the size of the conventionalncapsule preparations. The fenofibrate-containing compositionncomprises the following formula:n (a) fenofibrate 100 parts by weight, (b) a solid surfactant 3 to 4 parts by weight, (c) lactose 1 to 2 parts by weight, and (d) magnesium stearate 1 to 2 parts by weight, nin admixture with a binder and a disintegrator, wherein the sumnof said binder and said disintegrator is 17 to 20 parts bynweight, and the fenofibrate and the solid surfactant arenco-micronizates. |