abstract |
A pharmaceutical composition for performingntreatment against a skin disease, the pharmaceuticalncomposition comprising at least one decoy and anpharmaceutically acceptable carrier. The at least one decoynmay be selected from the group consisting of an NF-κB decoy,na STAT-1 decoy, a GATA-3 decoy, a STAT-6 decoy, an AP-1 decoynand an Ets decoy. The at least one decoy may be annoligonucleotide including at least two decoys bonded to eachnother, the at least two decoys being selected from the groupnconsisting of an NF-κB decoy, a STAT-1 decoy, a GATA-3 decoy,na STAT-6 decoy, an AP-1 decoy and an Ets decoy. The skinndisease may be atopic dermatitis, psoriasis vulgaris, contactndermatitis, keloid, bedsore, ulcerative colitis, or Crohn'sndisease. |