| abstract |
Compounds of formula (I) or a pharmaceutically acceptable salt thereofn nwherein:n V is selected from the group consisting of a covalent bond and CH 2 ; W is selected from the group consisting of a covalent bond, CH 2 and CH 2 CH 2 ; X is selected from the group consisting of a covalent bond and CH 2 ; Y is selected from the group consisting of a covalent bond, CH 2 and CH 2 CH 2 ; Z is selected from the group consisting of CH 2 and CH 2 CH 2 , and CH 2 CH 2 CH 2 ; L 1 is selected from the group consisting of a covalent bond and (CH 2 ) n ; n is 1-5; R 1 is selected from the group consisting of (a), (b), (c), (d), (e), (f), (g), (h), (i),n(j), (k), and (l); R 2 is selected from the group consisting of hydrogen, alkoxycarbonyl, alkyl,naminoalkyl, aminocarbonylalkyl, benzyloxycarbonyl, cyanoalkyl, dihydro-3-pyridinylcarbonyl,nhydroxy, hydroxyalkyl, phenoxycarbonyl, and -NH 2 ; nare useful for controlling synaptic transmission in mammal. |