| abstract |
The present invention provides a compound of the formula (I):n nwherein R 1a , R 1b , R 1c and R 1d are each independently hydrogen, lower alkyl, lowernalkenyl, lower alkynyl, lower alkylsulfonyl or cycloalkyl and the like, R 4 to R 15 arenhydrogen, halogen, hydroxy, lower alkyl, lower alkoxy, carboxy, lower alkoxycarbonyl,namino, nitro, lower alkylsulfonyl, lower alkylsulfonyloxy and the like, nwhich has superior immunosuppressive and /or anti-allergic activity and is useful for anpharmaceutical composition. |