abstract |
An alkanoic acid derivative useful as a prophylactic orntherapeutic agent of diabetes mellitus, hyperlipidemia,nimpaired glucose tolerance and the like can be provided by ancompound represented by the formulan nwherein R 1 is an optionally substituted 5-membered aromaticnheterocyclic group; X is a bond and the like; Q is a divalentnhydrocarbon group having 1 to 20 carbon atoms; Y is a bond andnthe like; ring A is an aromatic ring optionally further havingn1 to 3 substituents; Z is -(CH 2 ) n -Z 1 - (n is an integer of 1 to 8nand Z 1 is an oxygen atom and the like) and the like; ring B isna pyridine ring optionally further having 1 to 3 substituents,nand the like; U is a bond and the like; W is a divalentnhydrocarbon group having 1 to 20 carbon atoms; and R 3 is -OHnand the like, provided that, when ring B is a benzene ringnoptionally further having 1 to 3 substituents, U should be anbond, or a salt thereof. |