abstract |
(20S) esters of camptothecin analogs are provided. The compounds are (20S) esters of an oxyalkanoic acid and camptothecin, which <?delete-start id="DEL-S-00001" date="20070626" ?>is<?delete-end id="DEL-S-00001" ?> <?insert-start id="INS-S-00001" date="20070626" ?>are <?insert-end id="INS-S-00001" ?>optionally substituted at the 7, 9, 10, 11, and 12 positions of the camptothecin ring. The compounds are useful for treating cancer. |