http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1351911-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_829789af311640b53de23b9f5c8218a0 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C43-23 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C41-30 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C41-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C43-23 |
| filingDate | 2001-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2006-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_08c32ac7725258ba0862f4b91448de3b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a36ea5f4fb1230aaf5500699b563ed2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b78acf6181d2a1921928ccfb5f1deac8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_42a55e6813da6cfcc8bf70820cae83ab http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4eb84987c6500bff8312888a1a0f0cd6 |
| publicationDate | 2006-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1351911-B1 |
| titleOfInvention | Materials and methods for synthesizing stilbenes |
| abstract | The present invention relates materials and methods for synthesizing stilbenes, and in particular to processes for the synthesis of substituted stilbenes such as combretastatin A4. The present invention relates in particular to methods which are stereoselective for either the cis or the trans isomer of the substituted stilbene, using a Perkin-type condensation of an arylacetic acid and a substituted benzaldehyde, followed by a decarboxylation reaction to produce the substituted cis-stilbenes or a Suzuki-type reaction involving a Z or E-ethenyl halide and a substituted boronic acid in the presence of a palladium catalyst to produce specifically either the Z or E-isomer of substituted stilbenes. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102557998-A |
| priorityDate | 2000-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 131.