| abstract |
The present invention intends to provide a novel protein useful for anscreening of agonists/antagonists. Specifically, the present inventionnprovides rat- and mouse-derived protein or its salt, DNA encoding thenprotein, a determination method of ligand to the protein, a screeningnmethod and a screening kit for a compound that alters a binding propertynbetween ligand and the protein, a compound or its salt obtainable by thenscreening, and the like. n The protein of the present invention or the DNA encoding the samencan be used for, (1) a determination of ligand to the protein of the presentninvention, (2) a prophylactic and/or therapeutic agent for diseasesnassociated with dysfunction of the protein of the present invention, (3) anscreening of a compound (agonist/antagonist) that alters a bindingnproperty between the protein of the present invention and ligand, and thenlike. |