| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ebb8b1fb05e13f5e7922e38935bf2e9b |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 |
| filingDate |
2001-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2012-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c155aca64c86c9421cc65d0b62eee7c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eb82145defedbc6546b5a71557ece753
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17c198d6ae601397c79e3d4316e97360 |
| publicationDate |
2012-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1343802-B1 |
| titleOfInvention |
Process for the preparation of oligonucleotides |
| abstract |
A process for the synthesis of phosphorothioate oligonucleotides is provided which comprises assembling an aligonucleotide bound to to a solid support in the presence of acetonitrile; prior to cleaving the oligonucleotide from the solid support removing the acetonitrile; and cleaving the oligonucleotide from the solid support. The process is particularly suited to the large scale synthesis of nucleotides. The acetonitrile may be removed from the solid support by one or both to drying and by washing with solvents. Preferred washing solvents comprise trialkylamines. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9833761-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10907274-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10936953-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10583415-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11492728-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11332740-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11263354-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11562103-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10744477-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10053688-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11559778-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10696965-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11745159-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11550939-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10894242-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10987648-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11185837-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10632445-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10639609-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11732294-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10844373-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11691118-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11492665-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11377676-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10669304-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11697668-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10894959-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11512347-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11492727-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9981239-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10272410-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10975372-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9895673-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10754994-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11332738-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10618024-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11407837-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11452980-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10773232-B2 |
| priorityDate |
2000-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |