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filingDate 2002-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e63912e4419e7a6d0be718d7315b0f5
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publicationDate 2003-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1342779-A1
titleOfInvention Means and methods for manipulating hypersensitivity-like responses
abstract Immunoglobulin light chains (lg-LC) are produced in excess in animals compared to heavy chains. The present invention implicates these Ig-LC in hypersensitivity responses and provides means and methods for manipulating the responses. The invention further provides a common gamma chain independent receptor on mast cells capable of mediating the mentioned effects of Ig-LC. In response to activation of the pathway of which the found receptor is a part, a mast cell is activated and stimulated to degranulate.
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