abstract |
This invention relates to: an indole derivative or a pharmaceutically acceptable salt thereof represented by formula (I):n wherein R 1 is, for example, hydrogen or C 1-5 alkyl; R 2 is, for example, hydrogen or hydroxy; R 3 is, for example, hydrogen or hydroxy, -Z- is a crosslinkage having 2 to 5 carbon atoms; m is an integer from 0 to 3; n is an integer from 0 to 10; R 4 and R 5 are, for example, fluoro or hydroxy; R 9 is, for example, hydrogen or C 1-5 alkyl; and R 10 and R 11 are bound to each other to form, for example, -O-; and a pharmaceutical composition comprising the same, particularly a drug acting on δ opioid receptor. |