| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_10e4b1416c6e66e0ade5429212414964 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-282
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5021 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F1-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-42 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-50 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B53-00 |
| filingDate |
2001-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72a688dcc4eb8896dfc3680194158510
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5419ebfa5e24854e2502d9ca6deb3248
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b5d4afd97b446ba1ed49b117d53bd2e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7afc4a54821136b8819770dbe63017c3 |
| publicationDate |
2004-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1341785-A4 |
| titleOfInvention |
HYDROLYSIS OF ACID ESTERS R (R *, R *)] - 2- (4-FLUOROPHENYL) - $ g (b), $ g (d) -DIHYDROXY-5- (1-METHYLETHYL) -3-PHENYL -4- (PHENYLAMINO) CARBONYL] -1H-PYRROLE-1-HEPTANOIQUE USING CALCIUM HYDROXIDE HYDROXIDE |
| abstract |
The present invention provides a process for preparing atorvastatin hemi-calcium from an atorvastatin ester derivative with calcium hydroxide. The process is conveniently incorporated into a process for preparing atorvastatin hemi-calcium from an acetonide protected, ester protected β,δ-dihydroxy heptanoic acid precursor compound by a first acid hydrolysis step followed by base hydrolysis with calcium hydroxide. The latter process may be performed as a one-pot process. |
| priorityDate |
2000-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |