http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1339667-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cd2955c27933428d2aa5701f1ba09d5c |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D301-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C229-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D303-36 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D303-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D301-02 |
| filingDate | 2001-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a46b1d19eea5758bee113c352089f51d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8de31b3c4961418fc819630ab2f4b02b |
| publicationDate | 2003-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1339667-A1 |
| titleOfInvention | Process for the preparation of protected 1-(1-aminoalkyl)-oxiranes |
| abstract | A method is described for the preparation of a compound of formula (formula see on enclosed paper version) where R is a protective group of the amino groups of the amino acids; R' is a C1-C10 alkyl radical, an aryl, an aralkyl or a group ArX(CH2)m; where Ar is an aryl, X = O, S, NR'; R' is a C1-C5 alkyl or aryl radical and m is an integer between 0 and 5; in which (a) the carboxyl group of a compound of formula (formula see on enclosed paper version) is activated by treatment with a group that is an activator of carboxyl groups; (b) the compound thus activated is made to condense with a trimethylsulphoxonium or tri-methylsulphonium ylide; (c) the keto-ylide thus obtained is reduced by reaction with a ketone-reducing agent; (d) the compound thus obtained is then cyclized to give the compound of formula IV by reaction with a base. |
| priorityDate | 2000-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 110.