| abstract |
The invention relates to an arrangement for the production, testing and archiving of chemical or biological arrays bonded to a solid phase. The aim of the invention is to define such an arrangement which guarantees a locally-defined, temporary binding of individual solid phase supports to a common base support and simultaneously permits a transformation of the individual solid phase supports, according to a protocol, whereby any complete combined array or a subset thereof can be generated. Said aim is achieved, whereby a base support is formed from a large-surface support plate with a planar or arched surface form. Said base support (2) is provided with a number of discrete regions of elevated magnetic field strength, each of which permits a detachable attachment and retention of a solid phase support (1), each comprising a corresponding magnetic or magnetisable element (11), associated with a region of elevated magnetic field strength, such as a magnetic element (21) on the base support (2). The curvature of the surface of the solid phase support (1), facing the base support surface, matches the curvature of the base support surface to give a flush fit and the solid phase support (1) facing away from the base support surface (2) is provided with a functional layer (12) for the permanent bonding of chemical or biological substances. |