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filingDate 2000-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17ca8446b4316f1584ef6f480963c645
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publicationDate 2003-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1336850-A1
titleOfInvention Improved method for the detection of acid resistant microorganisms in a stool
abstract The invention relates to a method for detecting an infection of a mammal with an acid-resistant microorganism, wherein (a) a stool sample of the mammal is incubated using (aa) a receptor under conditions which involve complex formation of an antigen from the acid-resistant microorganism allow the receptor; or (ab) two different receptors are incubated under conditions which allow complex formation of an antigen from the acid-resistant microorganism with the two receptors and wherein the receptor according to (aa) or the receptors according to (ab) specifically bind / bind an antigen which at least in some of the mammals after the intestinal passage has a structure which corresponds to the native structure or the structure against which a mammal after infection or immunization with the acid-resistant microorganism or an extract or lysate thereof or a protein thereof or a fragment thereof or produces a synthetic peptide antibody; and (b) detects the formation of at least one antigen-receptor complex according to (a). The acid-resistant microorganism is preferably a bacterium, in particular Helicobacter pylori, Helicobacter hepaticus, Campylobacter jejuni or Mycobacterium tuberculosis. It is further preferred that the receptor (s) bind to an epitope / epitopes of a catalase. The invention further relates to diagnostic and pharmaceutical compositions and test devices which contain the aforementioned components and packaging containing them.
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priorityDate 1999-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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