abstract |
The invention provides methods and compositions relating to novelnpentafluorobenzenesulfonamide derivatives and analogs and their use asnpharmacologically active agents. The compositions find particular use asnpharmacological agents in the treatment of disease states, particularly atherosclerosisnand hypercholesterolemia, or as lead compounds for the development of such agents.nThe compositions include compounds of general formula (I). |