http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1334092-A4
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ac9442e962452275a63c777abad46223 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D451-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D451-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F3-14 |
| filingDate | 2001-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b13cc3c4935e840a69602a64be8dbdb3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e23ea20ea53cb2e6174b3753cdb1645d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e33a5a0f813e865839f1fbaf9c4df0de |
| publicationDate | 2004-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1334092-A4 |
| titleOfInvention | PROCESS FOR THE PREPARATION OF BICYCLIC AND POLYCYCLIC MOLECULES |
| abstract | A method of synthesis of a bicyclic or polycyclic compound of formula (I) or formula (II) in which: E represents an electrophile; each of R, R1, R2, R3, R6, R7, R8, R9 and X independently represents the common organic substituent groups defined in claim 1; Y represents C(r12)R13, O, NR14, or S; Z represents O, NR15, S or CR16W´; G represents W or X; W represents an electron withdrawing group; X has the same definition as R, and W´= W; and each of n and m represents an integer from O to 100. The method comprises the steps of (a) activating a compound of formula (III); 8b) subjecting a compound of formula (IV) to nucleophilic addition with the activated form of compound III; (c) subjecting the product of step (b) to ring closing metathesis; and (d) subjecting the product of step (c) to stereoselective ring closure. The methods of invention are useful in the synthesis of candidate pharmaceutical agents or intermediates in drugs synthesis. |
| priorityDate | 2000-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 199.