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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-85
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F3-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C17-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-85
filingDate 2001-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f8b80c8a542972d5a98a4e131ec65c54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0557fa1e9f1e730ecc64bc3357411599
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publicationDate 2003-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1334080-A1
titleOfInvention 1,3-bis(trifluoromethyl)benzene derivatives
abstract A method of manufacture of 3,5-bis(trifluoromethyl)bromobenzene, comprising the addition of a brominating reagent to a mixture of 3,5-bis(trifluoromethyl)benzene together with at least one of sulphuric acid or oleum in the absence of acetic acid. A method of production of 3,5-bis(trifluoromethyl)acetophenone comprising the reaction of 3,5-bis(trifluoromethyl)phenyl magnesium bromide with acetyl chloride in the presence of cuprous chloride. A method of production of 3,5-bis(trifluoromethyl)acetophenone comprising the steps of reacting 3,5-bis(trifluoromethyl)phenyl magnesium bromide with acetic anhydride, adding water, and recovering the product by azeotropic distillation. A method of removal of impurities including 3,5-bis(trifluoromethyl)acetate, 4-bromobutyl acetate and 4-chlorobutyl acetate from a preparation of 3,5-bis(trifluoromethyl)acetophenone, the method comprising heating the 3,5-bis(trifluoromethyl)acetophenone with a dilute solution of alkali. A method of production of 3,5-bis(trifluoromethyl)phenyl magnesium bromide comprising the reaction of 3,5-bis(trifluoromethyl)bromobenzene with magnesium in a solvent whilst maintaining the temperature of the reactants above 20 °C and below the reflux temperature of the solvent.
priorityDate 2000-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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