http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1333849-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_578d94c30b0b9c3ff4f81f829fe65fcf http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fdaa64756184e715af6cb25ebc318917 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4711 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| filingDate | 2001-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf311e5ed3909d6d8e4a643fe8afc185 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc9c4a23b42d97f1b84e152ec0360d14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a9ea36fa46624c83c8c1522063276aef |
| publicationDate | 2003-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1333849-A2 |
| titleOfInvention | Amyloid precursor protein and app-derived peptides inhibit tumor growth and metastasis |
| abstract | Amyloid precursor protein and non-glycosylated peptides derived therefrom especially from the Aβ domain of amyloid precursor protein are useful in prevention or treatment of cancer, and for immunostimulation in individuals with comprised immune systems. A peptide comprising residues 1-42 of the amyloid precursor protein, as well as smaller fragments and analogs of this peptide, which demonstrate the anti-cancer activity, are disclosed. A peptide comprising residues 1-16 of the amyloid precursor protein is one currently preferred active fragment. Pharmaceutical compositions comprising these peptides, and methods of using them to prevent or inhibit tumor growth and metastases are disclosed. Methods of gene therapy using APP or APP-derived peptides are also disclosed for treatment of cancer and for immunostimulation. |
| priorityDate | 2000-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 152.