Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_635cf51a1fb2f85ca9e89b335314423e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0711c29fb2da9b1dd808f0dc5cbcc14f |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-414 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-252 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-606 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2250-0067 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-86 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate |
2001-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_52fa4903a47f8af517000c631f3e3000 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ac51336d51859891e5382c4cac41b33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9947f0f2b76d52b2b55363c18fbc314f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f41717f0538e7ec9ee6562cbec234534 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4863eacea45c9006be38374f77bdaa90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab45065f645aa3615ca5a01322b6a415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9414320eb9e9aef6b4471f644925b5ba |
publicationDate |
2003-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-1330273-A1 |
titleOfInvention |
Coated implantable medical device |
abstract |
A medical device ( 10 ) includes a structure ( 12 ) adapted for introduction into a patient, the structure ( 12 ) being formed of a preferably non-porous base material ( 14 ) having a roughened or textured surface ( 16 ). The structure ( 12 ) is conveniently configured as a vascular stent with a base material ( 14 ) of stainless steel, nitinol or another suitable material. The medical device ( 10 ) also includes a layer ( 18 ) of a bioactive material posited directly upon the roughened or textured surface ( 16 ) of the base material ( 14 ) of the structure ( 12 ). The surface ( 16 ) of the base material ( 14 ) is roughened or textured by etching or by abrasion with sodium bicarbonate or another suitable grit. A preferred roughened or textured surface ( 16 ) is thought to have a mean surface roughness of about 10 muin. (about 250 nm) and a surface roughness range between about 1 muin. and about 100 muin. (about 25 nm and about 2.5 mum). The particularly preferred use of sodium bicarbonate as the abrasive to provide roughness or texture to the surface ( 16 ) of the base material ( 14 ) of the structure ( 12 ) is additionally advantageous in the low toxicity of the sodium bicarbonate to production workers, the ease of product and waste cleanup, and the biocompatibility of any residual sodium bicarbonate. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9730820-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011024614-A1 |
priorityDate |
2000-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |