| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5618863d71433f29d6051f86986e982a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2002-445
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2002-4445 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3691
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-227
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3604
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3658 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-40 |
| filingDate |
2001-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_187b86fa8c2d189ac0cbd69bf22ad1eb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3c3c63bd44893ef4a74778c1ff9c069
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7350709b2ba6382a77934589d656989 |
| publicationDate |
2009-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1328220-A4 |
| titleOfInvention |
IN-SITU BIOPROTHESIS FILLER AND ASSOCIATED METHODS, IN PARTICULAR FOR THE IN-SITU FORMATION OF INTERVERTEBRAL DISC BIOPROTHESES |
| abstract |
Bioprosthetic devices (10) include an exterior biological tissue member (10-1) which at least partly defines a cavity, and a proteinaceous biopolymer (10-2) which fills the cavity, and intercalates and is chemically bound (fixed) to the tissue of the surrounding biological tissue member. In preferred forms, the bioprosthetic device (10) is a bioprosthetic vertebral disc, having a fibrillar outer annulus which surrounds and defines an interior cavity and is formed by removal of at least a substantial portion of the natural gelatinous core therefrom. The cavity defined by the fibrillar outer annulus may then be filled with a flowable proteinaceous biopolymer (10-2). Preferably, the proteinaceous biopolymer (10-2) is a liquid mixture comprised of human or animal-derived protein material and a di- or polyaldehyde, which are allowed to react in situ to form a cross-linked biopolymer within the cavity. The liquid mixture may be formed in advance of being introduced into the cavity, or may be formed simultaneously during introduction into the cavity. |
| priorityDate |
2000-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |