Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_12a9e9ce63eb0bbf3658453fb50a6d9b |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3513 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-0008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-0041 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-191 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-24 |
filingDate |
2001-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f64e1f255f8f41d10480c8dfaac4b07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a44a492c950029bad5e26385c2421a1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_afd763856fdc9bc760b280444ba665ba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_547b0055a5e84b09d01c15501bce5c46 |
publicationDate |
2003-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-1326646-A2 |
titleOfInvention |
Transferrin-polycation/dna complexes for the systemic treatment of tumour diseases using cytotoxic proteins |
abstract |
The invention relates to a DNA complex containing at least one DNA molecule and coding for at least one therapeutically effective protein having cytotoxic activity; and a transferrin-conjugated polycation, the zeta potential thereof being </=+15mV. The complex, in which a high proportion of transferrin shields the positive charge, enables therapeutic DNA to be transported to tumours in a targeted manner during the systemic treatment of tumour diseases. |
priorityDate |
2000-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |