http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1325776-A1

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filingDate 2001-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e14f38eb79e211c020d7f76f443f240
publicationDate 2003-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1325776-A1
titleOfInvention Semiconductor device for detecting organic molecules and method for measuring organic molecules using the same
abstract A semiconductor device for detecting organic molecules is providednand affords higher sensitivity and better durability with respect to syntheticntreatment of organic molecule probes. In one implementation, an organicnmolecule detecting semiconductor device 100 has pixels (includingnphotoelectric converters) 110 disposed on a front (first main side) 101A of ansilicon substrate 101, and recesses 112 in which DNA probes 161 are fixednare formed on a rear (second main side) 101B. Hence the bottoms of thenrecesses 112 serve as organic molecule probe disposition regions. Thenorganic molecule detecting semiconductor device 100 constitutes a back-incidentnframe transfer (FT) type of CCD solid-state imaging device. In thenanalysis of DNA or other organic molecules, there is no need for the separatenprovision of an optical system for reading the light produced from a targetn(e.g., DNA of a specified structure). The overall apparatus is more compactnand the manufacturing costs are reduced. Also, the pixels 110 formed bynsemiconductor manufacturing technology and the DNA probes 161 formed bynorganic chemical treatment are formed on mutually different sides.
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