http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1325744-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_75a4811e7eae15e0f1e32cc6a222ce30 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-381 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-381 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-02 |
| filingDate | 2001-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a569f55a23ad1d7ae4fb9322374dbd9 |
| publicationDate | 2003-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1325744-A1 |
| titleOfInvention | Remedies for retinal nerve diseases containing 1,2-ethanediol derivatives or salts thereof |
| abstract | 1,2-Ethanediol derivatives represented by thenfollowing general formula [1]:n nwherein R 1 is substituted or unsubstituted heterocyclicngroup; R 2 is a hydrogen atom or a hydroxyl-protectingngroup; R 3 is a hydrogen atom or a lower alkyl group;nnR 4 's and nR 5 's, which may be the same or different,neach represents a hydrogen atom or a lower alkyl group;nR 6 is substituted or unsubstituted amino or ammoniongroup; and n is an integer of 1-6; or salts thereofnexhibits a retinal neuroprotective action in a glaucomanmodel and a retinal ischemia-reperfusion rat model, andntherefore prevents the cell death of retinal neuronsnand are useful as agents for preventing and treatingnretinal neuropathy such as glaucoma, diabeticnretinopathy, retinal artery occlusion, retinal veinnocclusion, macular retina degeneration, retinopathy ofnprematurity, etc. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1614419-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1614419-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7897594-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8067406-B2 |
| priorityDate | 2000-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 230.