| abstract |
The present invention refers to a pharmaceutical composition suitable for thentransdermal or transmucosal administration of one or more active agents, in form of angel or a solution, comprising as a permeation enhancers a combination of:n a) saturated fatty alcohol of formula CH 3 -(CH 2 ) n -CH 2 OH or saturated fatty acid CH 3 -(CH 2 ) n -CH 2 COOHnwherein n is an integer number 8 + 22, preferably 8 + 12, mostnpreferably 10, or unsaturated fatty alcohol or fatty acid of formula: nCH 3 (C n H 2(n-1) )-OH or CH 3 (C n H 2(n-1) )-COOH wherein n is an integer number 8 + 22, b) a ternary vehicle or carrier consisting of a C 1 + C 4 alkanol, a polyalcohol innparticular propylenglycol and water, c) optionally also a monoalkylether of diethylenglycol. |