http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1318138-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0efa077d881a96aeb1e29b21ef1bbb58 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D339-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-317 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D339-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-675 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-66 |
| filingDate | 2002-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2004-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fce3f674189dcf7f41dd9bcc7c73ecc4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b93dd85c4da09bf04caa398900ec4110 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d23b7839d8a2ddf816e7db8566c7548e |
| publicationDate | 2004-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1318138-B1 |
| titleOfInvention | Process for the preparation of dihydroxycarboxylic acid esters in the absence of solvents |
| abstract | Production of dihydroxycarboxylic acid esters, by reaction of hydroxycarboxylic acid diesters with complex hydrides, is conducted in the absence of a solvent. <??>Production of dihydroxycarboxylic acid esters of formula (I) by reaction of hydroxycarboxylic acid diesters of formula (II) with complex hydrides is conducted in the absence of a solvent. <??>n = 1, 2, 3, 4, 5, 6 or 7; and <??>R<1> and R<2> = optionally substituted 1-20C alkyl, 2-20C alkenyl or alkynyl, 3-8C cycloalkyl, aralkyl, aryl, hetarylalkyl or hetaryl <??>An Independent claim is included for production of R-(+)- alpha -lipoic acid of formula (III) from (I) obtained as above (i.e. in the absence of solvent) by: <??>(1) converting (I) to its bis-sulfonic ester by reaction in an organic solvent with a sulfonic acid chloride and a tertiary nitrogen base; <??>(2) converting the ester thus obtained to R- alpha -lipoic acid ester by reaction in a polar solvent with sulfur and an alkali metal disulfide; and then <??>(3) converting the ester to the required product. |
| priorityDate | 2001-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 181.